The Dominguez-Escalante National Conservation Area is a 209,610-acre (848.3 km2) National Conservation Area located in western Colorado southeast of Grand Junction and northwest of Montrose. It is managed by the Bureau of Land Management (BLM), and was created as part of the Omnibus Public Land Management Act of 2009. In 2009 66,280 acres (26,820 ha) were also designated as the Dominguez Canyon Wilderness.
The Dominguez-Escalante National Conservation Area (NCA) encompasses canyons along the Uncompahgre Plateau along the Gunnison River. The southwest side of the NCA borders Uncompahgre National Forest. There are several trails and campsites in the NCA.